Immune Cell Schematic (IMAGE)

University of California - San Diego

Immune Cell Schematic

Caption

Schematic diagram showing how a subset of immune cells, named DN2a T cells, mature into DN2b T cells. The maturation of this step is among the earliest in immune cell development and is controlled by the forgotten DNA strands that allow the genome to change its architecture to induce the 'Big Bang' of T cell development. In the absence of the "forgotten strands" DN2a cells fail to mature and ultimately after accumulating additional mutations become malignant T cells also named leukemias or lymphomas.

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UC San Diego

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