3D Crystal Structure of C. diff Toxin B (IMAGE)

University of California - Irvine

3D Crystal Structure of C. diff Toxin B

Caption

On the left is an illustration of the deadly C. diff bacteria as seen under a microscope. The image on the right, resembling a question mark, is the first three-dimensional crystal structure of TcdB holotoxin, secreted by C. diff. TcdB is illustrated as a ribbon model superimposed with a transparent molecular surface. This structure provides a blueprint to develop new therapeutics and vaccines for the treatment of CDI.

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UCI School of Medicine

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