New Class Antiviral (IMAGE)

Penn State

New Class Antiviral

Caption

The mechanism of a new class of antiviral drug. The RNA polymerase enzyme (yellow) replicates the virus genome by incorporating one nucleotide (black) at a time. Nucleotide analogues (red) are designed as antiviral drugs that can disrupt the replication process. The antiviral drugs work by (1) incorporating mutations, (2) stopping the replication process, or (3) a newly discovered mechanism in which the RNA polymerase enzyme pauses and then backtracks.

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Penn State

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