HP1a and piRNA Biogenesis (IMAGE) Osaka University Caption HP1a functions predominantly to support piRNA biogenesis. HP1a represses splicing of piRNA precursor transcripts for successful processing into mature piRNAs. Credit Osaka University Usage Restrictions None License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.