BITFAM Schematic (IMAGE) University of Illinois Chicago Caption A schematic overview of the BITFAM machine learning system developed by researchers at UIC. User provided sequencing data ("Normalized scRNA-Seq gene expression") and existing data on transcription factor binding sites ("ChIP-seq TF-Target gene matrix") are analyzed to predict transcription factor activity ("Inferred TF activity") that can be leveraged for a broad range of analyses. Credit Genome Research, Attribution 4.0 International CC BY 4.0 license Usage Restrictions None License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.