Cryo-EM Structure of an Inflammasome (IMAGE)

DOE/Lawrence Berkeley National Laboratory

Cryo-EM Structure of an Inflammasome

Caption

Shown is a structure of the first three subunits of an inflammasome, which consists of the NAIP5 and NLRC4 immune proteins, captured using cryo-electron microscopy. The NAIP5 subunit of the inflammasome is bound to flagellin (shown in light purple), a protein that is part of the flagellum some bacteria use to move around.

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Nicole Haloupek/UC Berkeley

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