Embryonic Brain Role (IMAGE) Tufts University Caption New research from Tufts University biologists shows that the nascent brain shapes normal body patterning and protects against developmental defects while the brain itself is still developing and before the animal shows any behaviors. Without a brain, frog embryos exposed to a teratogen developed an abnormal, curled tail and spine. In contrast, embryos with brains developed normal tails and spines (inset) even after exposure to the same teratogen. Tufts researchers were able to rescue defects by administering treatments already approved for use in humans. Credit Celia Herrera-Rincon/Tufts University Usage Restrictions For non-commercial use only, with appropriate attribution. License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.