Getting Stiffer (IMAGE)
Caption
During early development in an embryo, the progenitor cells of many types of musculoskeletal tissue start out in close contact to each other and over time transition into an organized network of individual cells surrounded by an extracellular matrix. Throughout the course of embryo development, it gets stiffer due to increased amounts of matrix material and crosslinking.
Credit
The lab of Robert Mauck, Perelman School of Medicine, University of Pennsylvania
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