Microglia, Synapses, and Obesity (IMAGE)

Society for Neuroscience

Microglia, Synapses, and Obesity

Caption

Obesity leads to cognitive impairment by activating microglial cells, which consume otherwise functional synapses in the hippocampus, according to a study of male mice published in JNeurosci. The research suggests that microglia may be a potential therapeutic target for one of the lesser known effects of this global health epidemic on the brain.

Credit

Cope at al., <i>JNeurosci</i> (2018)

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