Enlarged Dendrites after Drug Reinstatement (IMAGE)

Medical University of South Carolina

Enlarged Dendrites after Drug Reinstatement

Caption

High-resolution confocal micrographs of the enlarged dendrites (green) in the D1-medium spiny neurons (D1-MSN) of an animal after drug reinstatement (RST). The red dots represent phospho focal adhesion kinase (p-FAK). MSN are neurons from the nucleus accumbens, a structure that has a significant role in the cognitive processing of motivation, aversion and reward and so has a significant role in addiction.

Credit

Image courtesy of Dr. Peter Kalivas and Dr. Garcia-Keller. Medical University of South Carolina

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