How Stress Shrinks Synapses (IMAGE) Yale University Caption Expression of a single gene dramatically decreases synaptic connections between brain cells. Yale scientists believe this may explain why people suffering from chronic stress and depression suffer loss of brain volume Credit Courtesy Yale University Usage Restrictions None License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.