Figure 1. In vivo minimally invasive optical biopsy of the mouse brain with OCM. (IMAGE)

Light Publishing Center, Changchun Institute of Optics, Fine Mechanics And Physics, CAS

Figure 1. In vivo minimally invasive optical biopsy of the mouse brain with OCM.

Caption

a, Minimum intensity projection sagittal images, or "slices", with different projection thicknesses in the coronal direction, show cortical cytoarchitecture and the corpus callosum (CC), without physical tissue slicing. b, OCM signal decay (left panel) and averaged coronal image (middle panel) show sub-cortical layers. CC: corpus callosum; Or: stratum oriens; Rad: stratum radiatum; DG: dentate gyrus.

Credit

by Jun Zhu, Hercules Rezende Freitas, Izumi Maezawa, Lee-way Jin, and Vivek J. Srinivasan

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