ECM Remodeling Leads to Fibrosis (IMAGE) Rockefeller University Press Caption Compared with a control skin wound (left), the ECM within a wound containing increased numbers of myofibroblasts (right) is more consistently organized into linear fibers, which increases the activation and release of a growth factor that promotes fibrosis. Credit Klingberg et al., 2014 Usage Restrictions Reporters may freely use these materials in news coverage, with the appropriate credit information. License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.