Engineered T cells Combat Cancer in Mice (IMAGE)

Virginia Commonwealth University

Engineered T cells Combat Cancer in Mice

Caption

Control mice (left panel) with prostate cancer show large areas of metastasis in the lungs (blue). When a subset of animals were treated with unmodified T cells (middle panel), the secondary tumors were smaller than in untreated mice. And when a separate group of mice received T cells engineered to produce MDA-7/IL-24 (right panel), metastases shrunk even more, in some cases down to nothing.

Credit

Shawn Wang, Ph.D.

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