Sandwich assay (IMAGE) University of California - Santa Cruz Caption The antigen test uses a novel fluorescent probe for optical detection on the chip. This illustration shows the full antigen-capture complex assembled as a sandwich assay on a magnetic bead; a linker on the probe is cleaved with ultraviolet radiation and the probe is released, leaving a single probe per antigen for detection. Credit (Image credit: Stambaugh et al., PNAS 2021 Usage Restrictions For use only with news coverage of this research License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.