Normal vs. Mutant Cardiomyocytes (IMAGE) Boston Children's Hospital Caption A mutant heart muscle cell (in green) surrounded by normal cells. The mutant cell lacks Srf, a master maturation gene. It is unable to grow in size and lacks the fine membrane invaginations that help coordinate muscle contractions (appearing as vertical striations in the normal cells). Credit Guo Y; et al. / Boston Children's Hospital Usage Restrictions please credit as indicated License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.