3-D Engineered Bone Marrow Makes Functioning Platelets (IMAGE)
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A team led by researchers at the Tufts University School of Engineering and the University of Pavia has reported development of the first three-dimensional tissue system that reproduces the complex structure and physiology of human bone marrow and successfully generates functional human platelets. Using a biomaterial matrix of porous silk, the new, scalable system is capable of producing platelets for future clinical use and also provides a laboratory tissue system to advance study of blood platelet diseases. Shown above are platelet-producing blood cells called megakaryocytes (blue) releasing filament-like
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Courtesy Tufts University
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