Under Stress (IMAGE) University of Pennsylvania School of Medicine Caption In cells under duress, stress granules (in magenta) form outside of the nucleus (in blue). TDP-43 protein in green (arrow) that cannot bind to PolyADP ribose (PAR) builds up in large clumps distinct from stress granules. Credit Leeanne McGurk, University of Pennsylvania; <em>Molecular Cell</em> Usage Restrictions None License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.