Rat Amygdala Pre- and Post-Antibiotics (IMAGE) University of California - San Diego Caption There are more neurons in the central amygdala of a rat with an intact gut microbiome (no antibiotic treatment) undergoing withdrawal from oxycodone (left) and fewer neurons in the central amygdala of a rat with a depleted gut microbiome depleted (due to antibiotic treatment) in withdrawal (right). A decrease in neurons recruited in the central amygdala could result in fewer withdrawal symptoms, leading to higher risk of drug abuse. Credit UC San Diego Health Sciences Usage Restrictions Caption and credit as indicated License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.