Study Uncovers Inherited Genetic Susceptibility Across 12 Cancer Typess (IMAGE)
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Researchers long have known that some portion of the risk of developing cancer is hereditary and that inherited genetic errors are very important in some tumors but much less so in others.
In a new analysis, researchers have shed light on these hereditary elements across 12 cancer types. The research confirmed the well-known heritability of breast and ovarian cancers and found a surprising inherited component to stomach cancer. The study also provides some needed clarity on the consequences of certain types of mutations in well-known breast cancer susceptibility genes, BRCA1 and BRCA2.
The study, from Washington University School of Medicine in St. Louis, appears Dec. 22 in the journal Nature Communications. In the graphic, Lung 1 is lung squamous cell carcinoma, and Lung 2 is lung adenocarcinoma.
Credit
Sara Dickherber
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