Figure 1: Schematic Images of Location and Features of Meningeal Lymphatic Vessels and Their Changes (IMAGE)
Caption
The waste of the brain is drained by the CSF and exits the brain through the mLVs at the skull base (basal mLVs). The basal mLVs are connected to the lymphatic system through a hole in the skull (skull foramen) and they have abundant lymphatic vessel branches with a finger-like protrusions. There exists a valve within the vessel structure of the basal meningeal lymphatic vessels that allows the lymph to flow in one direction. In particular, the basal meningeal lymphatic vessels are anatomically located in close proximity to the CSF and have structures favoring the absorption and drainage of the CSF. The CSF is cleared outside the central nervous system into the deep cervical lymph nodes after drainage from the basal meningeal lymphatic vessels. Figure B is a schematic diagram showing that the basal mLVs undergo a severe deformation process and that their functionality is impaired with age.
Credit
IBS
Usage Restrictions
Please indicate the credit.
License
Licensed content