Shar-Pei Puppy (IMAGE) University of Washington Caption A very wrinkled Shar-Pei puppy nuzzles a smoother-skinned companion. Tiny genomic variations in the dog genome seem to suggest whether a Shar-Pei will be wrinkled or smooth, and a rare genetic mutation was found only in the Shar-Pei and not in other dogs in a Jan. 11, 2010, study. Credit Alison L. Ruhe, Center for Veterinary Genetics, University of California, Davis Usage Restrictions For use only by news media and educational institutions, including museums. License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.