BACE1 Depletion Reverses Alzheimer's Disease in Mouse Model (IMAGE)

Rockefeller University Press

BACE1 Depletion Reverses Alzheimer's Disease in Mouse Model

Caption

The brain of a 10-month-old mouse with Alzheimer's disease (left) is full of amyloid plaques (red) surrounded by activated microglial cells (green). But these hallmarks of Alzheimer's disease are reversed in animals that have gradually lost the BACE1 enzyme (right).

Credit

Hu et al., 2018

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