Fig.1. Graphical Abstract (IMAGE)

Osaka University

Fig.1. Graphical Abstract

Caption

Authors identified the plasma cell-prone LZ GC B cells whose generation relies on the amount of D40 signal. Higher expression of ICAM-1 and SLAM in those cells facilitates more stable contacts with Tfh cells, suggesting that strength of Tfh-GC B cell interaction critically regulates formation of plasma cell precursors.

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Osaka University

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