Delivering AAV into the Eye (IMAGE)

University of California - Berkeley

Delivering AAV into the Eye

Caption

Adeno-associated viruses (AAV) engineered to target specific cells in the retina can be injected directly into the vitreous of the eye to deliver genes more precisely than can be done with wild type AAVs, which have to be injected directly under the retina. UC Berkeley neuroscientists have taken AAVs targeted to ganglion cells, loaded them with a gene for green opsin, and made the normally blind ganglion cells sensitive to light.

Credit

John Flannery, UC Berkeley

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