Response of Mouse Brain to Cocaine (IMAGE) Nagoya University Caption Illustration of the pathway by which dopamine may induce reward. Dopamine activates dopamine receptor 1 (DA1R), which initiates a biochemical chain of events leading to excitation. Credit Nagoya University Usage Restrictions None License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.