Figure 1 Schematic illustration of human-induced pluripotent stem cell-derived functional enterocyte-like cells (IMAGE)

Tokyo Institute of Technology

Figure 1 Schematic illustration of human-induced pluripotent stem cell-derived functional enterocyte-like cells

Caption

Human-induced pluripotent stem cells derived enterocyte-like cells exhibit P-gp- and BCRP-mediated efflux and cytochrome P450 (CYP3A4)-mediated metabolism. We concluded that hiPS cell-derived enterocyte-like cells can be used as a model for the evaluation of drug transport and metabolism studies in the human small intestine.

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Tokyo Tech

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