Mre11 Bound to DNA (IMAGE)

DOE/Lawrence Berkeley National Laboratory

Mre11 Bound to DNA

Caption

Mre11 proteins initiate the repair of double-strand breaks in DNA, either on two ends of broken DNA brought together (synaptic complex at left) or at the site of a collapsed fork in replicating DNA (branching complex at right). The detailed structural information in these models was mostly obtained from protein crystallography of Mre11 dimers bound to DNA.

Credit

Williams, Tainer et al, Lawrence Berkeley National Laboratory and Scripps Research Institute

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