Antibody Footprints (IMAGE)

Purdue University

Antibody Footprints

Caption

These images illustrate antibody "footprints" outlined in yellow on the surface of a virus called EV71. Three distinct proteins - out of a total of 180 - that make up the viral capsid are outlined in blue, green, and red. The neutralizing antibodies E18 (A) and E19 (B), used in this study were found to bind to the viral proteins where the colors are bright. The E18 antibody causes the viral capsid to open, resulting in the loss of the viral genome, suggesting the virus no longer has the ability to replicate in the human host.

Credit

(Department of Biological Sciences, Purdue University)

Usage Restrictions

None

License

Licensed content

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.