Sensitive New Assay Detects Hepatitis B Infection in Single Liver Cells and Serum (IMAGE)

Elsevier

Sensitive New Assay Detects Hepatitis B Infection in Single Liver Cells and Serum

Caption

Hepatitis B virus (HBV) closed circular DNA (cccDNA) detection is of major clinical significance. HBV entry into the nucleus of liver cells (hepatocytes) stimulates cccDNA to create HBV RNAs that give rise to virus offspring. Measurement of cccDNA levels can help clinicians determine the level of HBV infection.

Credit

Song-Mei Liu

Usage Restrictions

None

License

Licensed content

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.