Mice and liver (IMAGE)
Caption
After being placed on high-fat diets, mice were either selected to take the PDE9 inhibiting oral drug or a placebo. The PDE9 inhibitor reduced total body and liver fat in mice without altering diet or physical activity. However, mice taking the placebo continued to gain body and liver fat throughout the 6-8-week drug trial.
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Images courtesy of David Kass
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