Graphical Abstract (IMAGE)

Cincinnati Children's Hospital Medical Center

Graphical Abstract

Caption

Obesity driven steatotic liver microenvironment through the activation of CXCR3 axis gives rise to a distinct population of inflammatory hepatic Th17 (ihTh17) cell subset, which preferentially utilizes the glycolytic pathway and PKM2 activity to fuel tissue inflammation and promote NAFLD progression.

Credit

Cincinnati Children's

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