AMYLOID 1 (IMAGE)
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Using computational models and atomic force microscope experiments, researchers at the University of Houston and Rice University have identified a possible “Achilles’ heel” in the frustration of amyloid beta peptides as they dock to the fibrils that form plaques in patients with Alzheimer’s. The frustrated steps could open a window for drugs able to cap the fibril ends, preventing further aggregation.
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Illustration by Yuechuan Xu/Peter Vekilov/University of Houston
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