Broadly Neutralizing Antibodies 10-1074 and 3BNC117 Each Bind to a Differen tSite on the SHIV Spike (IMAGE)

NIH/National Institute of Allergy and Infectious Diseases

Broadly Neutralizing Antibodies 10-1074 and 3BNC117 Each Bind to a Differen tSite on the SHIV Spike

Caption

This protein-structure model shows how the broadly neutralizing antibodies 10-1074 (blue) and 3BNC117 (red) that were infused into the monkeys each bind to a different site on the SHIV spike (beige and pink), helping prevent the virus from escaping the antibodies.

Credit

Gristick et al., <i>Nature Structural & Molecular Biology</i> 2016.

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