Squamous cells (IMAGE)

Cold Spring Harbor Laboratory

Squamous cells

Caption

Squamous cells make up the outer layer of several organs, such as skin, tongue, and esophagus. This image shows a tumor from a patient with squamous cell carcinoma. The cancer cells overproduce a cancer-causing version of the protein p63, called ∆Np63α (stained brown in this image). High levels of ∆Np63α make cancer cells become more like stem cells, which results in aggressive tumors.

Credit

Matt Fisher/Mills lab/CSHL, 2021

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