Figure 1 (IMAGE) Nagoya City University Caption The present study reveals that periplocin, a natural compound isolated from Periploca calophylla stem extracts, suppresses all three UPR branches (ATF6, IRE1, and PERK pathway). Credit © Muneshige Tokugawa Usage Restrictions None License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.