Pathological Hallmarks of AD (IMAGE)

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Pathological Hallmarks of AD

Caption

Shown here are the pathological hallmarks of Alzheimer's disease, beta-amyloid plaques (brown spots), as seen both in brain and retinal tissues from deceased patients, as described in the Aug. 17 edition of Journal of Clinical Investigation Insight (Koronyo et al. 2017). The structures of these plaques in the brain and retina are very similar (classical and vascular-associated deposits; bv = blood vessel), suggesting that the retina faithfully represent the brain disease.

Credit

Image adapted from <i>JCI Insight</i>. 2017; 2(16):e93621. doi:10.1172/jci.insight.93621 Retinal amyloid pathology and proof-of-concept imaging trial in Alzheimer's disease Yosef Koronyo ... Keith L. Black, Maya Koronyo-Hamaoui Published Aug. 17, 2017 Citation Information: <i>JCI Insight</i>. 2017;2(16):e93621. doi:10.1172/jci.insight.93621

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