Genetic deletion of Piezo1 in T cells leads to protection in autoimmunity (IMAGE)

University of California - Irvine

Genetic deletion of Piezo1 in T cells leads to protection in autoimmunity

Caption

Genetic deletion of Piezo1 in T cells leads to protection in autoimmunity: In the absence of Piezo1, Tregs expand more and, due to their increased numbers, are more effective in containing the damage inflicted by the effector T cells during an autoimmune neuroinflammation. Effector T cell function is not affected in the absence of Piezo1.

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UCI School of Medicine

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