Satb1 Controls the Pathogenic Function of Th17 Cells via Regulation of Bhlhe40 and PD-1 Expression (IMAGE)

Osaka University

Satb1 Controls the Pathogenic Function of Th17 Cells via Regulation of Bhlhe40 and PD-1 Expression

Caption

Satb1 is indispensable for the effector functions of pathogenic Th17 cells, including GM-CSF and IL-17 production via regulation of Bhlhe40 and PD-1 expression, respectively, in a murine autoimmune disease model.

Credit

Osaka University

Usage Restrictions

None

License

Licensed content

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.