Thioketal Nanoparticles (IMAGE) Georgia Institute of Technology Caption When delivered orally, thioketal nanoparticles remain stable in the harsh environment of the gastrointestinal tract, protecting siRNA and preventing its release to non-inflamed tissues (top). However, at sites of intestinal inflammation where unusually high levels of reactive oxygen species are present, the thioketal nanoparticles degrade and release siRNA to the site of inflammation (bottom). Credit Scott Wilson Usage Restrictions None License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.