VCP Inhibitors Revert Pathology Seen in IBMPFD Diseased Fruitflies (IMAGE)

University of California - Los Angeles

VCP Inhibitors Revert Pathology Seen in IBMPFD Diseased Fruitflies

Caption

In IBMPFD diseased fruit flies, muscles are damaged and mitochondria severely disrupted. (Red circles highlight representative damaged mitochondria.) Treatment of VCP inhibitors in these diseased flies reverts muscle pathology and rescues mitochondrial damage. (Green circles highlighting representative rescued mitochondria.)

Credit

Ting Zhang and Ming Guo

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