Toxic Shutdown (VIDEO) Ohio State University This video is under embargo. Please login to access this video. Caption New research shows how bacterial toxins are able to cripple normal cellular activity. Here, we see a slowdown in activity of formins (black specks, visible) at the tips of actin filaments (invisible) in the presence of active ACD toxin (top panels.) The lower panels show normal activity. Credit Ohio State Usage Restrictions credit Ohio State License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.