A CD3 -- Control Vehicle (IMAGE)

Institute for Research in Biomedicine (IRB Barcelona)

A CD3 -- Control Vehicle

Caption

Image A shows a metastatic tumor neglected by the immune system. Image B is taken after the inhibition of TGF-beta (Galunisertib), leading to the infiltration of many immune cells (in brown). And image C shows the result of the inhibition of TGF- beta plus immunotherapy (antibodies against PD-L1); this combination of treatments potentiates the activity of the immune system against the metastatic tumor.

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(Author: Daniele Tauriello, IRB Barcelona)

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