CD33 and Beta-Amyloid in Control and Knockout Mice (IMAGE)

NIH/National Institute of Mental Health

CD33 and Beta-Amyloid in Control and Knockout Mice

Caption

Activity of a regulator protein called CD33 (green) clogs removal of brain-damaging debris, beta-amyloid protein (red), by support cells, microglia. Microglia of normal control mice (A") show more CD33 and less beta-amyloid than mice in which CD33 expression is experimentally knocked-out (B").

Credit

Rudolph Tanzi, Ph.D., of Massachusetts General Hospital and Harvard University

Usage Restrictions

None

License

Licensed content

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.