Skinny Mouse on High-Fat Diet (IMAGE)

Washington University School of Medicine

Skinny Mouse on High-Fat Diet

Caption

Washington University researchers activated the Hedgehog protein pathway in the fat cells of mice. After eight weeks of eating a high-fat diet, mice that had been engineered with genes to activate the pathway didn't gain weight (left), but control animals whose Hedgehog pathways were not activated became obese (right).

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Washington University School of Medicine

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