The principle behind FPIA for detection of antibodies against SARS-CoV-2 (IMAGE)

Hokkaido University

The principle behind FPIA for detection of antibodies against SARS-CoV-2

Caption

The principle behind FPIA for detection of antibodies against SARS-CoV-2. When free fluorescently-labelled recombinant SARS-CoV-2 spike proteins (F-RBD) are exposed to a specific wavelength of polarized light, they emit depolarized light. However, if F-RBD are bound to anti-RBD antibodies, they emit polarized light instead, which can be measured (Keine Nishiyama, et al. Biosensors and Bioelectronics. June 5, 2021).

Credit

Keine Nishiyama, et al. Biosensors and Bioelectronics. June 5, 2021

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