Lower JIP3 Levels Enhance Amyloid Plaque Formation (IMAGE) Rockefeller University Press Caption In the brains of mice with Alzheimer's disease, decreased levels of JIP3 (right) induce the formation of larger amyloid plaques (red) and increased numbers of swollen axons filled with lysosomes (green). Credit Gowrishankar et al., 2017 Usage Restrictions Reporters may freely use these materials in news coverage with the appropriate credit information. License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.