6 inch-[<sup>18</sup>F]Fluoromaltotriose, a New PET Imaging Agent that Visualizes Valvular Infection (IMAGE)

Society of Nuclear Medicine and Molecular Imaging

6 inch-[<sup>18</sup>F]Fluoromaltotriose, a New PET Imaging Agent that Visualizes Valvular Infection

Caption

PET/CT imaging of a Staphylococcus aureus-induced endocarditis mouse model with 6 inch-[18F]Fluoromaltotriose showed that the heart had the highest PET signal above the diaphragm (as it was the source of infection), while the kidneys had the highest signal below the diaphragm. Within the heart, the PET signal from the infected aortic valve had the highest uptake and could be clearly seen; in some cases, the tricuspid valve was also infected (similar to what is seen for intravenous drug users).

Credit

Sanjiv Sam Gambhir, MD, PhD, Stanford University School of Medicine, Stanford, CA.

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