TIRF on metasurface (IMAGE)

Kyushu University

TIRF on metasurface

Caption

A mouse fibroblast cell imaged on a metasurface made of gold nanoparticles under a total internal reflection fluorescence (TIRF) microscope exhibits enhanced and confined emission from light-emitting paxillin protein at focal adhesions near the membrane. Researchers at Kyushu University have shown that such metasurfaces can be used with conventional fluorescence microscopes as a simple route to improve the resolution to near the diffraction limit. The use of TIRF conditions helps to reduce stray emission from deep within the cell to further improve contrast of structures near the metasurface.

Credit

Kaoru Tamada, Kyushu University

Usage Restrictions

Only for media and non-commercial use.

License

Licensed content

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.