Chandelier Cells Selectively Engaging with Local Neurons (IMAGE)
Caption
The CSHL team traced local and long-range connections of chandelier cells in the mouse brain. Arrow heads point to two of the chandelier cell soma or cell bodies, from each of which hundreds of candelabra-like arbors reach out to connect with local pyramidal neurons in a part of the cerebral cortex. These spatially intermixed excitatory neurons segregated into two groups, distinguished according to where in the brain they project to and their likely function. The chandelier cell can inhibit one group, causing a fear reaction to stop; from the other group it receives high-level information from elsewhere in the cortex that presumably informs its inhibitory activity.
Credit
Huang Lab, CSHL
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